Although the term “neurotoxin” is used to describe products like Botox, Dysport, Xeomin, and Jeuveau, we don’t always associate this term with friendly, age-defying anti-wrinkle injections. In fact, the phrase has a bit of a frightening connotation- think deadly biological warfare or sinister plots of espionage! (Maybe this is why many prefer to use the more friendly term “neuromodulator,” instead.)
The truth is that medications like Botox are actually made from one of the most poisonous substances known to mankind: botulinum toxin. 1 The smallest of doses can be fatal. Botulinum toxin is a natural protein produced by certain types of Clostridium bacteria. It blocks neurotransmitter release at the nerve-muscle junction, thereby paralyzing the muscle.
There are 4 neurotoxins approved by the FDA for anti-wrinkle injections: Botox, Dysport, Xeomin, and Jeuveau. They all are a neuromodulating drug that relaxes muscles and, most often, is used to reduce wrinkles in the skin. It’s derived from a bacterium, clostridium botulinum, that can be found in many different natural substances. When receiving neurotoxin injections in treatment, a small dose is given that lasts temporarily.